NFL Football Betting, or National Football League, is the biggest and the most popular league for American football Betting in the entire world, even though it is limited to the confines of the United States. The league was founded in 1920 as the American Professional Football Association, but after a few name changes and two years, landed with it's current and permanent name. The games played between the teams in this league (there are currently thirty two teams listed as league members) are some of the most popular sporting events in the USA, and are also beginning to gain popularity in other countries around the world, especially western European countries.

Not too long after the NFL Football league was formed, the games started getting popular, the NFL became a prime subject for sports betting punters, especially in the southern US. It is becoming more and more popular to participate in pre-season betting, where various matches and statistics for teams are opened up for bet placement weeks before the season even starts. Some people, who feel that they are mislead by their intuition about upcoming NFL Football Betting matches, prefer this type of gambling as it allows them to make a choice based only on the longer term as they have previous years statistics to go on.

One recent upset that came along with NFL football betting was the 2008 super bowl, where the New England Patriots were expected to win. When the Giants pulled of a surprising victory, many fans and gamblers alike where astounded. Those who participated in spread betting in favor of the New York Giants pulled in massive winnings; betting on the underdog sometimes really pays off.

Although worldwide the NFL Football Betting may not be as popular as soccer or horse racing, it is gaining in popularity as more people watch and bet on NFL football matches each and every season.